Wound healing is an important and still challenging task in modern medicine. In particular, the therapeutic options of treating chronic wounds linked to diseases like diabetes are limited. One promising approach is the application of cold atmospheric plasma (CAP) via medical plasma jets or dielectric barrier discharges to specifically stimulate the healing process of non-healing wounds. However, limitations occur regarding the treatment area in case of plasma jets. Thus, an innovative plasma jet array system (PJAS) was developed to extend the capabilities of established plasma jets in treating large chronic wounds. Utilizing a patented gas switching technology, the PJAS aims to provide an effective treatment over larger areas within shorter application times. The determination of performance and safety indicators included measurements of leakage current, temperature, OES and reactive species output. Values are compared with a medical plasma jet (PJ) system, the kINPen® MED. Findings indicated that the plasma jet array system showed enhanced efficacy compared to present medical plasma jets. Systematic analyses of leakage current, neutral gas temperature, and emission spectra confirmed the device's safety. A two-step observation was found in the effluent temperature profile of the PJAS with a possible relation to free jet physics and the argon enriched zones.
Field | Value |
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Group | |
Authors | |
Release Date | 2025-09-11 |
Identifier | bbe7bb2b-1a29-4b9c-a9d3-7cc773785bb6 |
Permanent Identifier (DOI) | |
Permanent Identifier (URI) | |
Is supplementing | |
Plasma Source Name | |
Plasma Source Application | |
Plasma Source Specification | |
Plasma Source Properties | Two sources were used: Multijet – titled "Plasma Jet Array System" PJAS for the paper. Voltage and Frequency go along with kINPen (~1MHz, 3-6 kV ptp) @ 1atm pressure. The device was available in two construction variations with two different Valve Settings. The PJAS operates a gas switching technology, where valves switch the argon supply to the designated channels at different flushing times. The two variations were: The final combination of device and setting together with association to respective measurements is mentioned as e.g. ‘PJAS I-2’ for PJAS device I at setting 2. |
Plasma Source Procedure | Plasma jets were flushed at least 15 minutes prior to performing diagnostics with argon, at least once per day. The device was mounted at a 0 mm distance by linear stages. For continous temperature measurements, motorized stages moved the temperature probe continously in front of a fixed plasma source. |
Plasma Medium Name | |
Plasma Medium Properties | Argon in ambient air at 1 atm and ~5atm pre-pressure; Temperature was around 20-25°C. Flow rate was controlled by mass flow control: F-201 CM with E-8412-A-10, 5 slm range, Bronkhorst, NL; despite the device having an internal flow control unit. |
Plasma Medium Procedure | Gas was flushed for at least 15 minutes before diagnostics initiation. |
Plasma Target Name | |
Plasma Target Properties | A copper plate was used as a target for the leakage current measurements.
There was no target used for the temperature measurements.
The target for the OES measurements was a conductive metal mesh.
A dielectric surface was used as the target for gas species determination. |
Plasma Target Procedure | Targets were mounted in plate holders from Thorlabs. Mounted on linear stages. In case of leakage current, a motorized stage (x,y,z, Thorlabs) was used for figure 4a and 4c. |
Plasma Diagnostics Name | |
Plasma Diagnostics Properties | Fiber optic temperature (FOT) analysis using a probe model TS5 (with 0.2 K precision, 0.55 mm out diameter) from Weidmann. |
Plasma Diagnostics Procedure | Temperature measurements. Patient leakage current. Optical emission spectroscopy. UV absorption spectroscopy |
Language | English |
License | |
Public Access Level | Public |
Contact Name | Gerling, Torsten |
Contact Email |
Data and Resources
- Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - TEMP PJAS CH1 (Fig. 4a)csv
Data table containing the temperatures measured for the kINPen Multijet...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - TEMP PJAS CH2 (Fig. 4a)csv
Data table containing the temperatures measured for the kINPen Multijet...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - TEMP PJAS CH3 (Fig. 4a)csv
Data table containing the temperatures measured for the kINPen Multijet...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - TEMP PJAS CH4 (Fig. 4a)csv
Data table containing the temperatures measured for the kINPen Multijet...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - TEMP PJ (Fig. 4c)csv
Data table containing the temperatures measured for the kINPen with fiber-...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - Neutral gas temperature with FOT PJAS device I-1 2.5 slm (Fig. 5a)csv
Data table containing the temperatures measured for the plasma jet array...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - Neutral gas temperature with FOT PJAS device I-1 5 slm (Fig. 5b)csv
Data table containing the temperatures measured for the plasma jet array...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - PLC PJAS device I-1 (Fig. 6a)csv
Data table containing the patient leakage current (PLC) measurement data for...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - PLC PJAS device I-2 (Fig. 6a)csv
Data table containing the patient leakage current (PLC) measurement data for...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - PLC PJAS device II-2 (Fig. 6a)csv
Data table containing the patient leakage current (PLC) measurement data for...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - PLC PJAS device I-1 all channels (Fig. 6b)csv
Data table containing the patient leakage current (PLC) measurement data for...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - OES N2 2.5 slm (Fig. 7a)csv
Data table containing nitrogen intensities measured by optical emission...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - OES N2 5 slm (Fig. 7a)csv
Data table containing nitrogen intensities measured by optical emission...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - OES Ar 2.5 slm (Fig. 7b)csv
Data table containing absolute (I) and relative (relI) argon intensities...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - OES Ar 5 slm (Fig. 7b)csv
Data table containing absolute (I) and relative (relI) argon intensities...
Preview Download - Safety and efficiency evaluation of an innovative plasma jet array in argon by gas switching technology - Ozone PJ and PJAS (Fig. 8)csv
Data table containing the ozone concentrations measured for the kINPen and...
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